Tonsils – the brain’s drain

Globally, more than 50% of all people are infected [8], with the prevalence of escalating with age. [9]

Helicobacter Pylori is a gram-negative bacterium that colonises within the human gastrointestinal tract (this includes the mouth).

Symptoms:

• Belching
• Nausea
• Vomiting
• Difficulty swallowing
• Abdominal discomfort
• Upper abdominal bloating
• Decreased appetite
• Peptic ulcers
• Bad breath
• Heartburn
• Reoccurring oral plaque
• Gingivitis
• Tooth cavities

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Risks:

• H. Pylori infection is the main cause of chronic gastritis, with an infection rate between 80%-95% in sufferers. [7]
• It is present in almost all cases of duodenal ulcers and most cases of gastric ulcer [10] with as many as 90% of individuals with ulcers being infected.
• H. Pylori is a significant contributing factor for the risk of gastric cancers.
• H. Pylori burrows deep within parietal cells (cells that secrete stomach acid), not only does this make it harder to eradicate, but this also leads to unique symptoms within the host. One factor being hypochlorhydria (low levels of stomach acid secreted within the body); this prevents the host from sterilising bacteria in food, reduces the ability to obtain nutrients desired from food and the inability to assimilate certain key minerals, such as zinc or iron.
• Reduced intrinsic factor (IF) production is also likely for individuals suffering from a H. Pylori infection. IF is essential to bind with vitamin B12, preventing further breakdown from stomach acid along with attaching to the surface of the ileum to allow for absorption of B12 into the body.
• H. Pylori can also block vitamin C absorption, thus compounding to the amount of oxidative damage inflicted onto the body.
• H. Pylori infection augments the gastric mucosal damage induced by NSAIDs.
• H. Pylori antagonises Aspirin-induced delayed ulcer healing due to suppression of acid secretion by the enhancement of PGE2 possibly derived by COX2 expression.
• Benefits:
  Due to the nature of the parasite being a gram-negative bacteria, it shifts the immune system more towards a Th1 mediated response as opposed to Th2 – this can reduce the severity of allergies, asthma and other humeral/mucosal reactions.

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Benefits:

Due to the nature of the parasite being a gram-negative bacteria, it shifts the immune system more towards a Th1 mediated response as opposed to Th2 – this can reduce the severity of allergies, asthma and other humeral/mucosal reactions.

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References:

1. Morales-Espinosa R, et al., Oral Microbiol Immunol. 2009
2. Nguyen AM, et al., Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995
3. Miyabayashi H, et al., Helicobacter. 2000
4. Gebara EC, et al., J Clin Periodontol. 2006
5. Dye BA, et al., Am J Public Health. 2002
6. Eskandari A, et al. Med Oral Patol Oral Cir Bucal.
7. Abro AH, et al. J Ayub Med Coll Abbottabad. 2011
8. Saudi J Gastroenterol. 2014
9. J Gastrointestin Liver Dis. 2011
10. J Gastroenterol Hepatol. 2011
11. Surveillance of Helicobacter pylori antibiotic resistance in England and Wales; Public Health England, 2008
12. Jernberg, C, et al. 2010

Trauma can lead to long lasting adaptive mechanisms to protect the individual from repeated exposure, usually these evolutionary defensive behavioural patterns continue later in life despite not being coherent to current day stressors. ⁣

This can lead to distorted situational awareness, disconnecting ones responses and actions from perceived ‘normative’ behaviour.⁣

Highly sensitive triggers may be running in the subconscious mind unknowingly to the individual.⁣

Studies show the adaptive response from trauma can extend over 14 generations. This is a huge component contributing to dysfunctional community syndrome and further stigmatisation.⁣

The following are common factors in trans-generational trauma:⁣

• Accidental’ epidemics⁣
• Massacres⁣
• Starvations⁣
• War⁣
• Slavery ⁣
• The removal of people to reserves ⁣

Below are examples of traumatic events:⁣

• African Slavery⁣
• The Holodomor⁣
• The Holocaust⁣
• World War 1⁣
• World War 2⁣
• Dutch Hunger Winter⁣
• Ritualistic Abuse⁣
• Aboriginal Australian Lineage⁣
• Childhood sexual abuse ⁣
• Middle Eastern War⁣

Do you think trans-generational trauma has impacted you in any way?

Have you suffered challenges to your mental health?

Depression has the third highest burden of all diseases in Australia (13%) [1] and also third globally [2].

Almost half (45%) Australians will experience a mental illness in their lifetime [3].

One in five, about 20%, Australians aged 16-85 experience a mental illness in any year:

• 11.5% have one disorder and 8.5% have two or more disorders.
• 14% of Australians suffer from anxiety disorders.
• 6% depressive disorders [4].

The age with the highest prevalence of mental illness is between 18-24 years of age.

21.2% of adolescents between 15-19 years of age met the criteria for a probable serious mental illness [5].

Six Australians die from suicide every single day, with a further 30 people will attempt to take their own life [6].

Suicide is the leading cause of death for people Australians aged 25-44 and the second leading cause of death for young people aged 15-24 [7].

Australians are more likely to die by suicide than skin cancer.

Indigenous Australians experience double the rate of suicide when compared to non-indigenous Australians [8].

The LGBT community experiences four times the rate when compared with those identified as heterosexual [9].

In 2011, men accounted for 76% of deaths from suicide [10], yet an estimated 72% of males don’t seek help for mental disorders.

54% of sufferers with mental illness do not seek treatment [1], which is only compounded by the delay in treatment due to problems with detection, social stigma and accurate diagnosis.

Individuals with mental illness accessing treatment are half that of people seeking treatment with physical disorders [11].It’s time to raise awareness for mental health.

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References

1. Australian Institute of Health and Welfare. (2014). Australia’s Health 2014. AIHW: Canberra.
2. World Health Organisation. (2008). The global burden of disease: 2004 update.
3. Australian Bureau of Statistics. (2009). National Survey of Mental Health and Wellbeing: Summary of Results, 4326.0, 2007. ABS: Canberra.
4. Kitchener, B.A. and Jorm, A.F. (2009). Youth Mental Health First Aid: A manual for adults assisting youth. ORYGEN Research Centre, Melbourne.
5. Ivancic, L., Perrens, B., Fildes, J., Perry, Y. and Christensen, H. (2014). Youth Mental Health Report, June 2014. Mission Australia and Black Dog Institute, Sydney.
6. The Australian Senate. (2010). The Hidden Toll: Suicide in Australia Report of the Senate Community Affairs References Committee. Commonwealth of Australia, Canberra.
7. http://www.aihw.gov.au/deaths/causes-of- death
8. Australian Bureau of Statistic. (2012). Australian Health Survey: First Results. ABS, Canberra.
9. National Mental Health Commission. (2013). A Contributing Life, the 2013 National Report Card on Mental Health and Suicide Prevention. NMHC, Sydney.
10. Department of Health and Ageing. (2013). National Mental Health Report 2013: tracking progress of mental health reform in Australia 1993 – 2011. Commonwealth of Australia, Canberra.
11. Commonwealth of Australia. (2010). National Mental Health Report 2010. Canberra, Australia.